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Join a community in Clayton
Experience the vibrant business culture of Clayton, a city in Missouri, with Spaces. Choose from serviced offices, coworking spaces, and meeting rooms in key areas like Downtown Clayton and Forsyth Boulevard. Our dynamic workspaces are designed for innovators and forward thinkers, ensuring you thrive in this professional environment.

Our thoughtfully crafted workspaces combine stunning design with vibrant communities. Every corner is curated to inspire big ideas and meaningful collaboration.
Join a thriving network of forward-thinking creators and businesses. Regular events, workshops, and social gatherings help you build relationships that grow your ideas and your network.
From hot desks to dedicated offices, Spaces offers a wide range of flexible solutions. Scale your workspace effortlessly as your team or ambition grows.
Enjoy smooth, professional support from a team dedicated to making your workday seamless. We handle the details so you can focus on what matters most.
Discover spaces crafted for creativity and connection throughout Clayton












Find your ideal workspace, wherever work takes you.
Nestled in the vibrant heart of Missouri, Clayton's downtown central business district is a magnet for top-tier businesses. High-rise office buildings dominate the skyline, offering a mix of office space for rent that caters to the needs of legal, financial, and consulting firms. The presence of major employers such as Centene Corporation underscores Clayton's reputation as a professional powerhouse. Forsyth Boulevard, a key arterial route, is lined with premium serviced offices and restaurants, providing easy access to public transportation via the Clayton and Forsyth MetroLink stations. These transport links ensure seamless connectivity to the greater St. Louis area, making Clayton a strategic location for businesses seeking growth and efficiency.
Clayton offers a dynamic range of workspaces that cater to various business needs. From sophisticated coworking spaces that foster collaboration among forward thinkers, innovators, and game changers, to fully-equipped meeting rooms designed to impress clients and facilitate productive gatherings. Maryland Avenue is known for its boutique shops and cafes, adding a touch of charm to the workday. Here, professionals can enjoy a blend of work and leisure, with Shaw Park providing a nearby recreational retreat. The emphasis on community engagement and networking is evident through local business associations that thrive in this area.
Clayton's strategic location is bolstered by excellent transport links and a plethora of amenities. Easy access to Interstate 64 and other major highways ensures that businesses are well-connected both locally and regionally. The proximity to renowned medical facilities like Barnes-Jewish Hospital and St. Mary's Hospital adds an extra layer of convenience for businesses prioritizing employee well-being. With a variety of upscale dining options, retail establishments, and wellness centers, Clayton offers a comprehensive environment that supports professional and personal growth. Whether you need a prestigious business address or a vibrant coworking space, Clayton provides the perfect backdrop for your business ambitions.
Can I use a Spaces location as my business address in Clayton?
Yes — a professional business address is included with our office space plans and Dedicated Desk plans.
If you don’t need a physical office, establish a presence with:
Business Address — optional mail handling and forwarding
Virtual Office Plans — add call answering and workspace access
For guidance on company registration rules in Clayton, please review here.
Do you have coworking desks in Clayton?
We do. Spaces coworking is designed for flexibility and focus — ideal for individuals and hybrid teams — with 13 locations to choose from in Clayton. Learn more here.
Our coworking range in Clayton includes:
Want ultimate mobility across the region and beyond? Choose a Cowork All Access Plan — 5, 10, or unlimited days per month across United States and our wider global network.
Whatever your workspace needs in Clayton, we’ll match you to the right hub. Contact us to find out more about coworking in Clayton.
Do you offer meeting rooms in Clayton?
Yes — configurable rooms across 13 local centers in Clayton. Explore details here. We support:
Meeting rooms — plug-and-play for client sessions and team huddles
Conference rooms — AV-ready for hybrid and video meetings
Boardrooms — premium settings with catering options
Interview rooms — private and discreet
Collaboration Rooms — writable walls and flexible layouts
Training rooms — classroom or U-shape with screens and whiteboards
Event spaces — from lounges to larger venues
From small groups to larger formats, we’ll configure the space to your agenda. contact us or check availability online.
Do you offer workspace for enterprises in Clayton?
Yes — many large organizations partner with Spaces across United States and globally for consistent quality, flexibility, and scale. Our enterprise solutions include:
Contact our enterprise team to align the right mix of spaces across your priority cities.
How do I visit a Spaces location in Clayton?
We’re happy to arrange a tour at any of our local hubs. If you’re exploring specific workspace types — offices, coworking, or event spaces — contact us and we’ll line up the best locations to view. For event attendees, your host can share arrival details and our reception team will welcome you.
I am an existing Spaces customer and have a question.
For center-specific questions, please reach out to your local team. For billing, plan changes, or agreement details, our support team can help here.
What are the opening hours for your centers in Clayton?
We’re happy to arrange a tour at any of our local hubs. If you’re exploring specific workspace types — offices, coworking, or event spaces — contact us and we’ll line up the best locations to view. For event attendees, your host can share arrival details and our reception team will welcome you.
What facilities and amenities are available at Spaces in Clayton?
All Spaces centers in Clayton are fully serviced — utilities, cleaning, and day-to-day operations included — so you can get to work immediately. Standard features include:
Select locations may also offer:
What offices do you offer in Clayton?
Spaces provides fully serviced offices for teams of every size — and you can choose from 13 centers in Clayton. Explore options here.
Our office space range in Clayton includes:
Every workspace can be tailored — layout, branding, furniture, storage, collaboration zones — and is move-in ready.
For short-term and on-demand use in Clayton, choose:
Need something industry-specific? See Specialized Spaces and our bespoke Industry Workspace Solutions.
Whatever your workspace needs in Clayton, our local footprint and global network make it easy to scale. contact us to find out more about offices in Clayton.
What support do you offer for specific industries in Clayton?
From energy and media to retail and manufacturing, we tailor environments to the way different sectors work — custom fit-outs, secure network rooms, sound-treated spaces, and layouts that flex with headcount. Explore solutions by industry and company size, or contact us to design a setup for your team.
Discover the Spaces range of offices, coworking desks, meeting rooms and virtual offices near you.
St. Louis
north_eastSt. Charles
north_eastKansas City
north_eastUniversity City
north_eastFlorissant
north_eastChesterfield
north_eastBreckenridge Hills
north_eastO'Fallon
north_eastLee's Summit
north_eastSt. Peters
north_eastIndependence
north_eastBlue Springs
north_eastColumbia
north_eastSpringfield
north_eastWentzville
north_eastJefferson City
Still have questions? Contact us, we’re happy to help!
Spaces contracts are not rental agreements, leases or tenancies. References on this site to “rent”, “rental” or “rental agreement” are used for convenience and search purposes only to describe the fees for workspace services and do not change the legal nature of the agreement you enter into.
All prices quoted are valid at the time of inquiry. Prices are subject to change and vary depending on the products and services selected, and subject to availability. Terms and conditions apply.
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7777 Bonhomme Avenue Downtown Clayton, Suite 1800, Clayton, MO, 63105, USA

7733 Forsyth Boulevard Downtown Clayton, 11th Floor, Clayton, MO, 63105, USA

4625 Lindell Boulevard Central West End, Suite 200 and 300, St. Louis, MO, 63108, USA

Two CityPlace Drive CityPlace Two, 2nd Floor, Creve Coeur, MO, 63141, USA

1031 Lami St, St. Louis, MO, 63104, USA

2055 Craigshire Rd Suite 410, St. Louis, MO, 63146, USA

111 West Port Plaza Maryland Heights, 6th Floor, St. Louis, MO, 63146, USA

12645 Olive Blvd 2nd Floor, Creve Couer, MO, 63141, USA

211 N Broadway - One Metropolitan Square, Saint Louis, MO, 63102, USA

100 South 4th Street Deloitte Building, Suite 550, St. Louis, MO, 63102, USA

3636 South Geyer Road Suite 100, Sunset Hills, MO, 63127, USA

3165 McKelvey Road 1st Floor, Bridgeton, MO, 63044, USA